Radiation damping artifacts in 2D COSY NMR experiments

✍ Scribed by G.E. Ball; G.J. Bowden; T.H. Heseltine; M.J. Prandolini; W. Bermel

• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Weight: 240 KB
• Volume: 261
• Category: Article
• ISSN: 0009-2614
• DOI: 10.1016/0009-2614(96)00987-6

✦ Synopsis

An experimental and theoretical analysis of multiple-quantum (MQ)-like artifacts in 2D NMR spectra of water is presented and discussed. During the t I domain, either magnetic field gradients or Q-switching techniques, were used to minimize radiation damping effects. Nevertheless, a myriad of MQ artifacts, in excess of A m = + 20, were observed in the indirectly detected t I domain. The source of these MQ-like artifacts has been traced, rather surprisingly, to radiation damping in the t 2 domain. This conclusion was reached experimentally, using Q-switching experiments in both the t I and t 2 domains, and confirmed theoretically, using a modification of the radiation damping theory of Vlassenbroek et al., J. Chem. Phys. 103 (1995) 5886.