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Radiation Combined With EGFR Signal Inhibitors: Head and Neck Cancer Focus

✍ Scribed by Paul M. Harari; Shyhmin Huang


Book ID
113900643
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
398 KB
Volume
16
Category
Article
ISSN
1532-9461

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## Abstract Epidermal growth factor receptor (EGFR), a receptor tyrosine kinase that activates multiple signaling pathways, including phosphatidylinositol‐3‐kinase/v‐AKT murine thymoma viral oncogene homolog protein (Akt), has long been a target of novel therapies. Despite universal EGFR expression