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RAD51 and XRCC3 polymorphism frequency and risk of myelodysplastic syndromes

✍ Scribed by Lisa M. Baumann Kreuziger; David P. Steensma


Book ID
101435522
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
196 KB
Volume
83
Category
Article
ISSN
0361-8609

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## Abstract Rad51‐mediated homologous recombination (HR) is essential for maintenance of genome integrity. The Xrcc3 protein functions in HR DNA repair, and studies suggest it has multiple roles at different stages in this pathway. Defects in vertebrate __XRCC3__ result in elevated levels of sponta