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RACEMIZATION IN PEPTIDE SYNTHESIS

✍ Scribed by BENOITON, N. LEO ;KURODA, KEIJI ;CHEN, FRANCIS M.F.


Book ID
115097635
Publisher
Wiley (Blackwell Publishing)
Year
2009
Tongue
English
Weight
259 KB
Volume
15
Category
Article
ISSN
0367-8377

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A new method has been developed for the rapid determination of D-cysteine contents in synthetic peptides. It is based on the reduction of cystine residues, when present, with tris-alkylphosphines, selective derivatization of the cysteine residues with 4-vinylpyridine, followed by acid hydrolysis of