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RAC1/P38 MAPK Signaling Pathway Controls β1 Integrin–Induced Interleukin-8 Production in Human Natural Killer Cells

✍ Scribed by Fabrizio Mainiero; Alessandra Soriani; Raffaele Strippoli; Jordan Jacobelli; Angela Gismondi; Mario Piccoli; Luigi Frati; Angela Santoni

Book ID
117722583
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
274 KB
Volume
12
Category
Article
ISSN
1074-7613

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## Abstract Matrix metalloproteinases (MMPs) are responsible for degradation of extracellular matrix and play important roles in cell migration, proliferation, and tissue remodeling related to airway inflammation. Interleukin‐1β (IL‐1β) has been shown to induce MMP‐9 production in many cell types a