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Quinazolinone derivatives. Kinetics of the reaction of 2-chloromethyl-3-hydroxy-4-(3H)quinazolinone with nucleophiles

✍ Scribed by Beatriz M. Fernandez; Celia B. Schapira; Samuel Lamdan


Book ID
112126023
Publisher
Journal of Heterocyclic Chemistry
Year
1980
Tongue
English
Weight
339 KB
Volume
17
Category
Article
ISSN
0022-152X

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## Abstract magnified image A series of 2‐substituted‐4(3__H__)‐quinazolinones **13‐20** has been synthesized in good yields using the reaction of double lithiated 2‐methylquinazolinone‐4 with a variety of aromatic aldehydes. They have been easily transformed in high yields into the corresponding