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Quaternization and dequaternization of pyrazoles in solvent-free conditions: Conventional heating versus microwave irradiation

✍ Scribed by Enrique Díez-Barra; Antonio De La Hoz; Ana Sánchez-Migallón; José Elguero

Publisher
Journal of Heterocyclic Chemistry
Year
1999
Tongue
English
Weight
363 KB
Volume
36
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

We report a study on the quaternization and dequaternization of pyrazoles by conventional heating and microwave irradiation in solvent‐free conditions. Microwave irradiation produces an acceleration in the quaternization rate and a rapid equilibration between quaternized and non quaternized products. Dequaternization is also more rapid and a change on the selectivity is observed using symmetric pyrazolium salts.

📜 SIMILAR VOLUMES

ChemInform Abstract: Quaternization and
ChemInform Abstract: Quaternization and Dequaternization of Pyrazoles in Solvent-Free Conditions: Conventional Heating versus Microwave Irradiation.
✍ Enrique Diez-Barra; Antonio de la Hoz; Ana Sanchez-Migallon; Jose Elguero 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Alkylation and arylation of pyrazoles un
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✍ Inés Almena; Enrique Díz-Barra; Antonio De La Hoz; Juliana Ruiz; Ana Sínchez-Mig 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 408 KB

## Abstract The use of sodium hydrogen carbonate under solvent‐free conditions and microwave irradiation is by far the best method for __N‐__alkylating pyrazoles. The yields are good and the method is devoid of side reactions (quaternization, isomerization, hydrogen halide elimination). Solvent‐fre