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Quaternary ammonium analogs of ether lipids inhibit the activation of protein kinase C and the growth of human leukemia cell lines

✍ Scribed by Francesca Civoli; Larry W. Daniel


Book ID
105994387
Publisher
Springer
Year
1998
Tongue
English
Weight
252 KB
Volume
42
Category
Article
ISSN
0344-5704

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Initial studies revealed that proline-directed protein kinase F A (PDPK F A ) was overexpressed in various cancerous tissues relative to normal controls. However, the functional role of overexpressed PDPK F A in cancer remains to be established. In this report, we explore the potential role of PDPK