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Quasi-linkage: a confounding factor in linkage analysis of complex diseases?

โœ Scribed by Sinthuja Sivagnanasundaram; KarlW. Broman; Michelle Liu; Arturas Petronis


Book ID
106133979
Publisher
Springer
Year
2004
Tongue
English
Weight
149 KB
Volume
114
Category
Article
ISSN
0340-6717

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## Abstract By adapting a wellโ€known affectedโ€relativeโ€pair linkage model that can incorporate covariate or subโ€phenotype information [Olson, 1999: __Am J Hum Genet__ 65:1760โ€“1769], we have developed a recursiveโ€partitioning (RP) algorithm (treeโ€based model) for identifying phenotype and covariate