𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Quantum Mechanical/Molecular Mechanical Investigation of the Mechanism of C−H Hydroxylation of Camphor by Cytochrome P450 cam : Theory Supports a Two-State Rebound Mechanism

✍ Scribed by Schöneboom, Jan C.; Cohen, Shimrit; Lin, Hai; Shaik, Sason; Thiel, Walter


Book ID
120968603
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
488 KB
Volume
126
Category
Article
ISSN
0002-7863

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Two-state reactivity mechanisms of hydro
✍ Sason Shaik; Samuël P de Visser; François Ogliaro; Helmut Schwarz; Detlef Schröd 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 199 KB

Recent computational studies of alkane hydroxylation and alkene epoxidation by a model active species of the enzyme cytochrome P-450 reveal a two-state reactivity (TSR) scenario in which the information content of the product distribution is determined jointly by two states. TSR is used to reconcile