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Quantitative subcellular study of transferrin receptor-targeted doxorubicin and its metabolite in human breast cancer cells

✍ Scribed by Xu, Jinhui; Sheng, Yuan; Xu, Feifei; Yu, Ying; Chen, Yun

Book ID
121585221
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
374 KB
Volume
39
Category
Article
ISSN
0378-7966

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## Abstract A transferrin receptor was demonstrated in tumor tissue from 10 patients with breast carcinoma and one patient with breast sarcoma. Binding studies were conducted by measuring the amount of ^125^I‐transferrin binding to microsomal preparations of the tumor tissue. Elevated levels of spe