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Quantitative Structure—Activity Relationship Studies on Inhibition of HERG Potassium Channels.

✍ Scribed by Katsumi Yoshida; Tomoko Niwa


Publisher
John Wiley and Sons
Year
2006
Weight
8 KB
Volume
37
Category
Article
ISSN
0931-7597

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## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al