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ChemInform Abstract: Comparative Quantitative Structure—Activity Relationship Studies on Anti-HIV Drugs

✍ Scribed by Rajni Garg; Satya P. Gupta; Hua Gao; Mekapati Suresh Babu; Asim Kumar Debnath; Corwin Hansch

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
31
Category
Article
ISSN
0931-7597

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HIV Protease Inhibitory Bis-benzamide Cyclic Ureas: A Quantitative Structure-Activity Relationship Analysis. -A series of about thirty title compounds, such as (V), is synthesized and evaluated for HIV protease inhibition and antiviral activity. Derivatives (V) show to be potent inhibitors of HIV p