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Quantitative Structure–Activity Relationship Modeling of Growth Hormone Secretagogues Agonist Activity of some Tetrahydroisoquinoline 1-Carboxamides

✍ Scribed by Julio Caballero; Fabio M. Zampini; Simona Collina; Michael Fernández


Book ID
111368378
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
147 KB
Volume
69
Category
Article
ISSN
1747-0277

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N-tert-Butyl-N,N@-dibenzoylhydrazines such as tebufenozide (RH-5992) mimic the action of a molting hormone, 20-hydroxyecdysone, and cause premature molting of larvae leading to their death. Previously, it was shown that one of the benzoyl moieties in dibenzoylhydrazines plays a role similar to that