✦ LIBER ✦

Quantitative structure–activity relationship and design of polysubstituted quinoline derivatives as inhibitors of phosphodiesterase 4

✍ Scribed by Anand Gaurav, Vertika Gautam, Ranjit Singh

Book ID: 118777994
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 630 KB
Volume: 21
Category: Article
ISSN: 1054-2523
DOI: 10.1007/s00044-011-9831-x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Design, Synthesis and Structure—Activity

Design, Synthesis and Structure—Activity Relationships of a Series of 9-Substituted Adenine Derivatives as Selective Phosphodiesterase Type-4 Inhibitors.

✍ Pierre Raboisson; et al. et al. 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 71 KB

CoMFA and CoMSIA 3D-quantitative structu

CoMFA and CoMSIA 3D-quantitative structure-activity relationship model on benzodiazepine derivatives, inhibitors of phosphodiesterase IV

✍ Pierre Ducrot; Charles R. Andrianjara; Roger Wrigglesworth 📂 Article 📅 2001 🏛 Springer Netherlands 🌐 English ⚖ 403 KB

Structure–Activity Relationship and Rati

Structure–Activity Relationship and Rational Design of 3,4-Dephostatin Derivatives as Protein Tyrosine Phosphatase Inhibitors

✍ Takumi Watanabe; Takayuki Suzuki; Yoji Umezawa; Tomio Takeuchi; Masami Otsuka; K 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 429 KB

Several alkyl-and O-methylated-3,4 -dephostatin were synthesized and evaluated for their inhibitory activity toward protein tyrosine phosphatase. Alkyl chains with a length up to that of the pentyl group gave tolerable inhibition, whereas methylation of hydroxyl groups resulted in a decrease in the

Design, Synthesis, and Structure–Activit

Design, Synthesis, and Structure–Activity Relationship of N -Arylnaphthylamine Derivatives as Amyloid Aggregation Inhibitors

✍ Di Santo, Roberto; Costi, Roberta; Cuzzucoli Crucitti, Giuliana; Pescatori, Luca 📂 Article 📅 2012 🏛 American Chemical Society 🌐 English ⚖ 629 KB

Design, synthesis, and structure–activit

Design, synthesis, and structure–activity relationships of pyrazole derivatives as potential FabH inhibitors

✍ Peng-Cheng Lv; Juan Sun; Yin Luo; Ying Yang; Hai-Liang Zhu 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 265 KB

Fatty acid biosynthesis is essential for bacterial survival. FabH, b-ketoacyl-acyl carrier protein (ACP) synthase III, is a particularly attractive target, since it is central to the initiation of fatty acid biosynthesis and is highly conserved among Gram-positive and -negative bacteria. Fifty-six 1

Design, synthesis, and quantitative stru

Design, synthesis, and quantitative structure–activity relationship of cytotoxic γ-carboline derivatives

✍ Jing Chen; Xiaowu Dong; Tao Liu; Jianshu Lou; Chaoyi Jiang; Wenhai Huang; Qiaoju 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 626 KB