Design, synthesis, and structure–activit
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Peng-Cheng Lv; Juan Sun; Yin Luo; Ying Yang; Hai-Liang Zhu
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Article
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2010
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Elsevier Science
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English
⚖ 265 KB
Fatty acid biosynthesis is essential for bacterial survival. FabH, b-ketoacyl-acyl carrier protein (ACP) synthase III, is a particularly attractive target, since it is central to the initiation of fatty acid biosynthesis and is highly conserved among Gram-positive and -negative bacteria. Fifty-six 1