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Quantitative structure-pharmacokinetic relationship modelling: apparent volume of distribution

✍ Scribed by Taravat Ghafourian; Mohammad Barzegar-Jalali; Nasim Hakimiha; Taravat Ghafourian; Mark T. D. Cronin


Book ID
111769073
Publisher
Pharmaceutical Press
Year
2004
Tongue
English
Weight
288 KB
Volume
56
Category
Article
ISSN
2042-7158

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The purpose of this study was to develop quantitative structure-activity/pharmacokinetic relationships (QSAR/QSPKR) for 11 selected corticosteroids in man. Multiple linear regression analysis with an automatic forward step-wise inclusion algorithm was used to construct QSAR/QSPKR models from molecul