✦ LIBER ✦

Quantitative structure-activity relationship study and directed synthesis of Thieno[2,3-d]pyrimidine-2,4-diones as monocarboxylate transporter 1 inhibitors

✍ Scribed by O. T. Devinyak, Mikh. V. Slivka, Mar. V. Slivka, V. M. Vais, V. G. Lendel

Book ID: 118777926
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 442 KB
Volume: 21
Category: Article
ISSN: 1054-2523
DOI: 10.1007/s00044-011-9748-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis and structure–Activity relatio

Synthesis and structure–Activity relationships of thieno[2,3-d]pyrimidine-2,4-dione derivatives as potent GnRH receptor antagonists

✍ Zhiqiang Guo; Yongsheng Chen; Dongpei Wu; Yun-Fei Zhu; R.Scott Struthers; John S 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 221 KB

The synthesis and SAR studies of thieno [2,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists to treat reproductive diseases are discussed. It was found that the 2-(2-pyridyl)ethyl group on the 5-aminomethyl functionality of the core structure was a key feature for good receptor binding ac

Synthesis and Structure—Activity Relatio

Synthesis and Structure—Activity Relationships of Thieno[2,3-d]pyrimidine-2,4-dione Derivatives as Potent GnRH Receptor Antagonists.

✍ Zhiqiang Guo; Yongsheng Chen; Dongpei Wu; Yun-Fei Zhu; R. Scott Struthers; John 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 92 KB 👁 2 views

ChemInform Abstract: Synthesis and Quant

ChemInform Abstract: Synthesis and Quantitative Structure-Activity Relationships of Antihyperlipaemic 2-Substituted Thieno(3,2-d)pyrimidin-4(3H)-ones.

✍ C. J. SHISHOO; K. S. JAIN; I. S. RATHOD; B. J. THAKKAR; S. B. BRAHMBHATT; T. P. 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB

Synthesis and Biological Activity of Pyr

Synthesis and Biological Activity of Pyrido[3′,2′:4,5]thieno[3,2- d ]pyrimidines as Phosphodiesterase Type 4 Inhibitors

✍ Taltavull, Joan; Serrat, Jordi; Gràcia, Jordi; Gavaldà, Amadeu; Andrés, Míri 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 924 KB

Design, Synthesis, and Biological Activi

Design, Synthesis, and Biological Activities of New Thieno[3,2-d]pyrimidines as Selective Type 4 Phosphodiesterase Inhibitors1

✍ Crespo, María I.; Pagès, Lluís; Vega, Armando; Segarra, Victor; López, Manel; Do 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 300 KB

ChemInform Abstract: Synthesis of New Th

ChemInform Abstract: Synthesis of New Thieno[2,3-d]pyrimidine-2,4(1H,3H)-diones with Analgesic and Antiinflammatory Activities.

✍ G. ROMEO; F. RUSSO; A. CARUSO; V. CUTULI; M. AMICO-ROXAS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 1 views