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Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects

✍ Scribed by Fabio Di Domenico; Rukhsana Sultana; Eugenio Barone; Marzia Perluigi; Chiara Cini; Cesare Mancuso; Jian Cai; William M. Pierce; D. Allan Butterfield

Publisher: Elsevier
Year: 2011
Tongue: English
Weight: 973 KB
Volume: 74
Category: Article
ISSN: 1874-3919
DOI: 10.1016/j.jprot.2011.03.033

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## Abstract Lectin affinity chromatography is a powerful separation technique that fractionates proteins by selectively binding to specific carbohydrate moieties characteristic of protein glycosylation type. Wheat germ agglutinin (WGA) selectively binds terminal N‐acetylglucosamine (O‐GlcNAc) and s