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Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors

✍ Scribed by Vera L Costa; Rui Henrique; Franclim R Ribeiro; Mafalda Pinto; Jorge Oliveira; Francisco Lobo; Manuel R Teixeira; Carmen Jerónimo

Book ID
115011013
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
349 KB
Volume
7
Category
Article
ISSN
1471-2407

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## Abstract ## BACKGROUND. Methylation‐mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and progression. Studies also have indicated that concordant methylation of multiple genes (methylator phenotypes), rather than a single g