Cancer cells are associated with global hypomethylation but with focal hypermethylation of specific gene promoters organized as CpG island. DNA methyltransferases, DNMT1 and 3 (3a and 3b), have been implicated in mediating maintenance and de novo methylation. Hypermethylation of gene promoters resul
Quantitative analysis of promoter hypermethylation in multiple genes in osteosarcoma
β Scribed by Peng Hou; Meiju Ji; Bin Yang; Zaozao Chen; Junjun Qiu; Xin Shi; Zuhong Lu
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 329 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0008-543X
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