Quantitative MR microscopy of enzymatically degraded articular cartilage
✍ Scribed by Miika T. Nieminen; Juha Töyräs; Jarno Rieppo; Juhana M. Hakumäki; Johanna Silvennoinen; Heikki J. Helminen; Jukka S. Jurvelin
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 293 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0740-3194
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We have developed an algorithm to estimate and display the spatial distribution of the thickness of articular cartilage in human knees. We used a simulation to derive the most appropriate formula for estimating thickness in digital images. The algorithm was tested by imaging a thickness phantom and
## Abstract ## Objective Calcitonin has been suggested to have chondroprotective effects. One signaling pathway of calcitonin is via the second messenger cAMP. We undertook this study to investigate whether increased cAMP levels in chondrocytes would be chondroprotective. ## Methods Cartilage de