Quantitative GLC determination of cyclophosphamide and isophosphamide in biological specimens
โ Scribed by C. Pantarotto; A. Bossi; G. Belvedere; A. Martini; M. G. Donelli; A. Frigerio
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 363 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
โฆ Synopsis
also be applicable to urine and plasma samples obtained after administration of conventional doses of the drug.
๐ SIMILAR VOLUMES
A method developed for measuring the antitumor agent ftorafur and its biotransformation product Muorouracil was applied to biological specimens. After extraction with ethylacetate, ftorafur, S-fluorouracil, and the internal standard 2-methyl-4-hydroxy-6-chloromethylpyrimidine are converted to their
ping m, methylenes and methines), 3.59 (s, 3H, vinyl methoxy), 3.64 and 3.66 (as, 3H total, carbomethoxy), 3.72 (d, lH, J = about 10 Hz, benzylic proton on C-41, 5.00 (s, lH, vinyl), 5.82 (s and an indistinct overlapping signal, 2H plus lH, methylenedioxy and proton on C-3), and 6. 64 and 6.67 (2s,