Quantitative gas chromatography/tandem mass spectrometry using resonant and non-resonant collisions in ion traps

✍ Scribed by Christian Andalò; Guido C. Galletti; Paola Bocchini

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 109 KB
• Volume: 12
• Category: Article
• ISSN: 0951-4198
• DOI: 10.1002/(sici)1097-0231(19981130)12:22<1777::aid-rcm380>3.0.co;2-a

✦ Synopsis

In ion trap mass spectrometry, collisional experiments are easily performed by precursor ion selection and software controlled operations. Collisional activation can be achieved by two different approaches, resonant and non-resonant excitation. Different results are usually obtained by the two approaches. Four related compounds of biological interest (lignin monomers), i.e. guaiacol (2-methoxyphenol), syringol (2,6-dimethoxyphenol), 4-allyl syringol (2,6-dimethoxy-4-allyl-phenol) and 4-syringaldehyde (4-hydroxy-3,5-dimethoxybenzaldehyde) have been studied by gas chromatography/tandem mass spectrometry. Sample concentration affects both single ion storage and collisional spectra of these compounds. The use of the two collisional approaches leads to different collision induced dissociation spectra of molecular species. The present work attempts to rationalize the observed behaviour.