Quantitative gas chromatography using a new automated derivatizer

✍ Scribed by Frank, H. ;Gerhardt, J. ;Nicholson, G. J.

• Book ID: 102345745
• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: English
• Weight: 418 KB
• Volume: 8
• Category: Article
• ISSN: 0935-6304
• DOI: 10.1002/jhrc.1240080811

✦ Synopsis

In the gas chromatographic analysis of complex biological samples, the most time-consuming and error-prone steps are the pretreatment required for isolation and purification of the compounds of interest and,for most analytes, thederivatization to chemically and thermally stable compounds with high volatility. These wet-chemical steps are usually carried out manually, and for routine analysis of large numbers of samples they are often rate-limiting. A dedicated automated derivatizer has been constructed, the employment of which significantly reduces the time required for manual labor and increases the reproducibility of derivatiration and hence the accuracy of analysis.