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Quantitative Fourier transform infrared/attenuated total reflectance analysis of ketoprofen in some pharmaceutical formulations

✍ Scribed by A. Van Overbeke; W. Baeyens; W. Van den Bossche


Book ID
103956860
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
580 KB
Volume
9
Category
Article
ISSN
0924-2031

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✦ Synopsis


An overhead attenuated total reflectance system was used to quantify ketoprofen in some pharmaceutical formulations (capsules and injection ampoules). No extensive sample pretreatment was needed. The ampoules were analysed as such and a simultaneous quantification of ketoprofen and arginine base was performed. A partial least-squares software package (PLS1) was applied to the calibration and prediction for a limited number of standard solutions.


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