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Quantitative dynamic contrast-enhanced MRI for mouse models using automatic detection of the arterial input function

✍ Scribed by Jae-Hun Kim; Geun Ho Im; Jehoon Yang; Dongil Choi; Won Jae Lee; Jung Hee Lee


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
757 KB
Volume
25
Category
Article
ISSN
0952-3480

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Gd-DTPA kinetics in arterial blood was investigated by dynamic MRI in 47 patients with malignant and benign mammary tumors. Signal enhancement was monitored for 10 min after the beginning of a 1-min infusion of 0.1 mmol/kg Gd-DTPA. Kinetics in blood was biexponential with median half-lives of 21 sec