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Quantitative determination of metoprolol in plasma and urine by gas chromatography

✍ Scribed by Ervik, Magnar


Book ID
114799173
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
321 KB
Volume
36
Category
Article
ISSN
0001-6683

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Determination of metoprolol in human pla
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## Abstract A simple, specific and sensitive HPLC method has been developed for the determination of metoprolol in human plasma and urine. Separation of metoprolol and atenolol (internal standard) was achieved on an Ace C~18~ column (5 μm, 250 mmΓ—4.6 mm id) using fluorescence detection with Ξ»~ex~=2