Matrix-assisted laser desorption/ionization time-of-flight mass spectra of proteins in cerebrospinal fluid analyzed without prior purification are presented. Less than 100 fmol amounts of proteins in the 10 000 to 20 000 u mass range and linked to human disease (multiple sclerosis, Alzheimer's disea
✦ LIBER ✦
Quantitative Analysis of β-Amyloid Peptides Expressed in Human Cerebrospinal Fluid by an Improved Method of Antibody-Assisted Time-of-Flight Mass Spectrometry
✍ Scribed by Akira Matsumoto; Reiko Matsumoto; Kei-ichi Kadoyama; Taka-aki Nishimoto; Shogo Matsuyama; Osamu Midorikawa
- Book ID
- 106452231
- Publisher
- Springer Netherlands
- Year
- 2009
- Tongue
- English
- Weight
- 265 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1573-3149
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## Improvement of an in-gel tryptic digestion method for matrix-assisted laser desorption/ionization-time of flight mass spectrometry peptide mapping by use of volatile solubilizing agents The combination of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS