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Quantitative analysis of the metabolism of 9,10-dihydrobenzo[a]pyrene by induced rat liver microsomes

✍ Scribed by Nesnow, Stephen; Jackson, Linda; Padgett, William T.; Lambert, Guy R.; Agarwal, Satish C.

Book ID
123086240
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
525 KB
Volume
73
Category
Article
ISSN
0304-3835

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex