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Quantitative Analysis of Hydroxymethylated DNA in Primary Colorectal Cancer

✍ Scribed by Kudo, Yotaro ;Tateishi, Keisuke ;Yamamoto, Keisuke ;Yamamoto, Shinzo ;Mohri, Dai ;Isomura, Yoshihiro ;Asaoka, Yoshinari ;Ijichi, Hideaki ;Omata, Masao ;Koike, Kazuhiko

Book ID
122179363
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
58 KB
Volume
140
Category
Article
ISSN
0016-5085

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We investigated and compared the DNA content between primary and metastatic lesions from 30 colorectal cancer cases. The findings were only diploid in 2 cases (6.7%) and only aneuploid in 18 cases (60.0%). On the whole, the DNA ploidy agreed in 20 cases (66.7%) between both lesions. In the 18 cases