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Quantitative analysis of adenosine A1 receptors in human brain using positron emission tomography and [1 -methyl-11C]8-dicyclopropylmethyl-1-methyl-3-propylxanthine

✍ Scribed by Yuichi Kimura; Kenji Ishii; Nobuyoshi Fukumitsu; Keiichi Oda; Toru Sasaki; Kazunori Kawamura; Kiichi Ishiwata


Book ID
116798805
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
283 KB
Volume
31
Category
Article
ISSN
0969-8051

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## N1-(111C]-Methyl>2-Br-LSD ([llC] -MBL) has been developed as a positron emission tomography (PET) imaging agent for serotonin 5-HT2 receptors. In vitro receptor binding assays with nonradioactive MBL show high-affinity binding to serotonin 5-HT2 receptors (Ki = 0.5 nM), a secondary interaction