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Quantitation of substitutions at amino acid 70 in hepatitis C virus genotype 1b

✍ Scribed by Zhongjie Hu,Ying Liu,Lixia Qiu,Zuopeng Fan,Wei Nie,Shan Liang…

Book ID
126377015
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
339 KB
Volume
11
Category
Article
ISSN
1743-422X

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Substitution of amino acid 70 in the hep
Substitution of amino acid 70 in the hepatitis C virus core region of genotype 1b is an important predictor of elevated alpha-fetoprotein in patients without hepatocellular carcinoma
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## Abstract Previous studies identified amino acid (aa) substitutions of the hepatitis C virus core region of genotype 1b (HCV‐1b core region) and elevated serum alpha‐fetoprotein (AFP) levels as predictors of poor virologic response to pegylated interferon (PEG‐IFN) plus ribavirin (RBV), and also