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Quantitation of Fc receptor-bearing T-lymphocytes (TG and TM) in oral cancer

✍ Scribed by Prabha Balaram; D. M. Vasudevan

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
318 KB
Volume
52
Category
Article
ISSN
0008-543X

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✦ Synopsis

The lymphocytes from the peripheral blood of 30 untreated patients with oral cancer and 15 apparently healthy normal controls were studied for quantitation of T-cell subsets. When compared to age-matched controls, the patients as a group showed a significant increase in the proportion and number of TG cells

(IgC Fc receptor-bearing T-cells) and a significant reduction in the TM cells (IgM Fc-bearing T-cells).

The levels of total lymphocytes, T-cells, and B-cells remained in the control range. The discrepancy in the TG subset was evident in the early stages of the disease, while in T M cells, it was evident only in the advanced stages.

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