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Quantitation of clonazepam and its 7-amino and 7-acetamido metabolites in plasma by high-performance liquid chromatography

โœ Scribed by Inga Petters; Dun-Ren Peng; Anders Rane


Book ID
108447908
Publisher
Elsevier Science
Year
1984
Weight
532 KB
Volume
306
Category
Article
ISSN
0378-4347

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Quantitation of urapidil and its metabol
โœ Nieder, M. ;Dilger, C. ;Haerlin, R. ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 382 KB ๐Ÿ‘ 1 views

The antihypertensive agent urapidil (Ebrantil Byk-Gulden, Konstanz) can be reliably quantitated with three metabolites in human serum using high performance liquid chromatography. Serum is alkalinized and extracted with ethyl acetate. The organic phase is back-extracted with diluted acid. An aliquot