Mitochondrial DNA analysis in Parkinson'
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Dr. A. H. V. Schapira; I. J. Holt; M. Sweeney; A. E. Harding; P. Jenner; C. D. M
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Article
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1990
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John Wiley and Sons
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English
β 479 KB
π 1 views
## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1βmethylβ4β