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Quantifying tetrapeptide SS-20 in rat plasma using hydrophilic interaction liquid chromatography coupled with electrospray ionization tandem mass spectrometry

✍ Scribed by Yan Zhan; Xiaoyan Chen; Dafang Zhong


Book ID
116620467
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
753 KB
Volume
879
Category
Article
ISSN
1873-376X

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## Abstract Hydrophilic interaction LC with MS/MS (HILIC‐MS/MS) was described as a rapid, sensitive, and selective method for the quantification of doxazosin in human plasma. Doxazosin and cisapride (internal standard) were extracted from human plasma with ethyl acetate at alkaline pH and analyzed