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Simultaneous determination of six alkaloids in blood and urine using a hydrophilic interaction liquid chromatography method coupled with electrospray ionization tandem mass spectrometry

✍ Scribed by Ximei Wu; Weixiong Huang; Lin Lu; Li Lin; Xingfen Yang


Book ID
105893539
Publisher
Springer
Year
2010
Tongue
English
Weight
450 KB
Volume
398
Category
Article
ISSN
1618-2650

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## Abstract A high‐performance liquid chromatographic–tandem mass spectrometric (HPLC–MS–MS) assay was developed and validated to determine quantitatively flocoumafen and brodifacoum in whole blood using warfarin as an internal standard (IS). Liquid–liquid extraction, using ethyl acetate, was used