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Quantification of Three Lidocaine Metabolites and Their Conjugates

✍ Scribed by Yun K. Tam; June Ke; Ronald T. Coutts; D. George Wyse; Murray R. Gray

Book ID
110342086
Publisher
Springer US
Year
1990
Tongue
English
Weight
698 KB
Volume
07
Category
Article
ISSN
0724-8741

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✍ Franz-Josef Leinweber; R. Clive Greenough; Frederick J. Di Carlo πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 English βš– 677 KB

Female beagles dosed once with encapsulated 14C-bunolol (10 mg/kg) excreted 61% of the isotope in urine in 24 hr. The pooled urine contained a minimum of 18 labeled compounds. Two previously unknown metabolites were purified and were identified by UV and mass spectral data; they were hydroxybunolol