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Quantification of the impact of HIV-1 reverse transcriptase and protease mutations on the efficacy of rescue HAART

✍ Scribed by Stefania Paolucci; Fausto Baldanti; Renato Maserati; Francesco Castelli1; Fredy Suter1; Franco Maggiolo1; Angelo Pan1; Giuseppe Gerna


Book ID
114144057
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
165 KB
Volume
45
Category
Article
ISSN
0166-3542

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## Abstract Therapeutic failures due to in vivo loss of drug sensitivity are still a major problem in AIDS care. Currently, the role of and methods for detecting resistant mutant strains in patients before therapeutic choices are still under debate. To investigate the relevance of screening for key