Quantitative analysis of gemcitabine tri
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S. A. Veltkamp; M. J. X. Hillebrand; H. Rosing; R. S. Jansen; E. R. Wickremsinhe
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Article
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2006
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John Wiley and Sons
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English
β 222 KB
## Abstract Gemcitabine triphosphate (dFdCTP) is a highly active metabolite of gemcitabine. It is formed intraβcellularly via the phosphorylation of gemcitabine by deoxycytidine kinase. The monitoring of dFdCTP in human peripheral blood mononuclear cells (PBMCs), in addition to plasma concentration