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Quantification of dopamine transporter density with [18F]FECNT PET in healthy humans

✍ Scribed by Nye, Jonathon A.; Votaw, John R.; Bremner, J. Douglas; Davis, Margaret R.; Voll, Ronald J.; Camp, Vernon M.; Goodman, Mark M.

Book ID
122333991
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
608 KB
Volume
41
Category
Article
ISSN
0969-8051

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We have characterized the usage of [ 18 F]CFT (also known as [ 18 F]WIN 35,428) as a radioligand for in vivo studies of human dopamine transporter by PET. CFT was labeled with 18 F to a high specific activity, and dynamic PET scans were conducted in healthy volunteers at various time points up to 5