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[18F]LBT-999, a new radioligand to study the dopamine transporter with PET: Characterization in baboons

✍ Scribed by Wadad Saba; M.-A. Schöllhorn; H. Valette; S. Chalon; F. Dolle; L. Garreau; P. Emond; J.B. Deloye; D. Guilloteau; M. Bottlaender

Book ID
118490039
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
50 KB
Volume
31
Category
Article
ISSN
1053-8119

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## Abstract LBT‐999 (8‐((__E__)‐4‐fluoro‐but‐2‐enyl)‐3‐beta‐__p__‐tolyl‐8‐aza‐bicyclo[3.2.1]octane‐2‐beta‐carboxylicacid methyl ester) is a recently developed cocaine derivative belonging to a new generation of highly selective dopamine transporter (DAT) ligands (__K__~D~: 9 nM for the DAT and IC~5

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