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Quantification of Benzodiazepine Receptors in Human Brain Using PET, [11C]Flumazenil, and a Single-Experiment Protocol

✍ Scribed by Delforge, Jacques; Pappata, Sabina; Millet, Philippe; Samson, Yves; Bendriem, Bernard; Jobert, Antoinette; Crouzel, Christian; Syrota, André


Book ID
118675629
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
742 KB
Volume
15
Category
Article
ISSN
0271-678X

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## Abstract The peripheral benzodiazepine receptor (PBR) is expressed by microglial cells in many neuropathologies involving neuroinflammation. PK11195, the reference compound for PBR, is used for positron emission tomography (PET) imaging but has a limited capacity to quantify PBR expression. Here