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Use of a standardized uptake value for parametric in vivo imaging of benzodiazepine receptor distribution on [11C]flumazenil brain PET

✍ Scribed by Masahito Tsukamoto; Chietsugu Katoh; Tohru Shiga; Tomohito Kaji; Yuji Kuge; Kunihiro Nakada; Nagara Tamaki


Book ID
105962153
Publisher
Springer
Year
2004
Tongue
English
Weight
347 KB
Volume
31
Category
Article
ISSN
0340-6997

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## Abstract The peripheral benzodiazepine receptor (PBR) is expressed by microglial cells in many neuropathologies involving neuroinflammation. PK11195, the reference compound for PBR, is used for positron emission tomography (PET) imaging but has a limited capacity to quantify PBR expression. Here