Quantification and clinical relevance of brain atrophy in multiple sclerosis: a review
✍ Scribed by Blandine Grassiot; Béatrice Desgranges; Francis Eustache; Gilles Defer
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 315 KB
- Volume
- 256
- Category
- Article
- ISSN
- 0340-5354
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## Abstract Magnetic resonance imaging (MRI) has been widely used to diagnose and monitor multiple sclerosis (MS). Although MRI‐visible lesions are a key feature of MS, they are thought to correlate poorly with clinical progression. Neurodegeneration is increasingly being recognized as an important
## Abstract ## Purpose To explore relations between spatial distribution of multiple sclerosis (MS) lesions, and disability. In MS, the presence of asymptomatic brain lesions challenges the prediction of disability based on conventional brain MRI. Hypothesizing that symptomatology may partly be de