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Quality and Quantity of Diffuse and Focal White Matter Disease and Cognitive Disability of Patients with Multiple Sclerosis

โœ Scribed by Giuseppe Bomboi; Vasiliki N. Ikonomidou; Stefano Pellegrini; Susan K. Stern; Antonio Gallo; Sungyoung Auh; Iordanis E. Evangelou; Jhalak Agarwal; Clelia Pellicano; Joan M. Ohayon; Fredric K. Cantor; Mary Ehrmantraut; Henry F. McFarland; Robert L. Kane; Francesca Bagnato

Book ID
109268485
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
197 KB
Volume
21
Category
Article
ISSN
1051-2284

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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation