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Increased water self-diffusion in chronic plaques and in apparently normal white matter in patients with multiple sclerosis

✍ Scribed by P. Christiansen; P. Gideon; C. Thomsen; M. Stubgaard; O. Henriksen; H. B. W. Larsson

Book ID: 114783854
Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 534 KB
Volume: 87
Category: Article
ISSN: 0001-6314
DOI: 10.1111/j.1600-0404.1993.tb04100.x

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## Abstract Oxidative stress has been implicated in the pathophysiology of multiple sclerosis (MS). Increased levels of reactive oxygen species (ROS) derived from infiltrating macrophages and microglial cells have been shown to reduce the levels of endogenous antioxidants and to cause the oxidation