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Qualitative changes of anticonvulsant action of felbamate during development in rats

✍ Scribed by Renata Haugvicová; Hana Kubová; Pavel Mareš

Book ID
117545829
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
136 KB
Volume
20
Category
Article
ISSN
0387-7604

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The anticonvulsant actions of lamotrigine and phenytoin against pentylenetetrazol-induced seizures were compared in laboratory rats during ontogenesis. Both drugs (lamotrigine in doses of 2.5, 5, 10, and 20 mg/kg and phenytoin in doses of 5, 10, 30 and 60 mg/kg) were injected intraperitoneally 30 mi