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Anticonvulsant Action of Topiramate Against Motor Seizures in Developing Rats

✍ Scribed by Renata Haugvicová; Hana Kubová; Markéta Škutová; Pavel Mareš

Book ID
109108398
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
541 KB
Volume
41
Category
Article
ISSN
0013-9580

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The anticonvulsant effectiveness of AHR-11748 (3-[3-(trifluoromethyl)phenoxy]-1-azetidinecarboxamide) was evaluated in the kindled amygdaloid seizure model in rats. Doses of AHR-11748 that did not cause prestimulation toxicity significantly attenuated elicited afterdischarge durations and the severi